An Amino-Terminal Fragment of lac Repressor Binds Specifically to lac Operator
โ Scribed by Ronald T. Ogata and Walter Gilbert
- Book ID
- 123655420
- Publisher
- National Academy of Sciences
- Year
- 1978
- Tongue
- English
- Weight
- 977 KB
- Volume
- 75
- Category
- Article
- ISSN
- 0027-8424
- DOI
- 10.2307/68855
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๐ SIMILAR VOLUMES
In the lac operon, the existence of a secondary repressor binding site, inside Z gene, had been inferred from in vitro binding studies (Reznikoff et al., 1974; Gilbert et al., 1975). A series of deletions have been constructed from a lac transducing lambda bacteriophage. Some of those deleted bacter
A model is suggested for the lac repressor binding to the lac operator in which the repressor polypeptide chain sequences from Gly 14 to Ala 32 and from Ala 53 to Leu 71 are involved in specific interaction with operator DNA. A correspondence between the protein and DNA sequences is found which expl