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An Alternative to Phosphotyrosine-Containing Motifs for Binding to an SH2 Domain

✍ Scribed by Mauricio Rojas; Songyi Yao; John P. Donahue; Yao-Zhong Lin

Book ID: 115580311
Publisher: Elsevier Science
Year: 1997
Tongue: English
Weight: 643 KB
Volume: 234
Category: Article
ISSN: 0006-291X
DOI: 10.1006/bbrc.1997.6694

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## Abstract A frequently used approach to transform peptides into more drug‐like compounds is preparation of the corresponding peptoids or peptide–peptoid hybrids. Although peptoids have advantages, there may also be some disadvantages such as their increased flexibility and the reduced ability for