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How and why phosphotyrosine-containing peptides bind to the SH2 and PTB domains

✍ Scribed by Yingyao Zhou; Ruben Abagyan

Book ID
114382729
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
288 KB
Volume
3
Category
Article
ISSN
1359-0278

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✍ F. J. Dekker; N. J. DE Mol; R. M. J. Liskamp 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 244 KB

## Abstract A frequently used approach to transform peptides into more drug‐like compounds is preparation of the corresponding peptoids or peptide–peptoid hybrids. Although peptoids have advantages, there may also be some disadvantages such as their increased flexibility and the reduced ability for