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An alternating selection strategy for cloning phage display antibodies

โœ Scribed by Jun Lu; Steven R Sloan

Book ID
114052218
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
166 KB
Volume
228
Category
Article
ISSN
0022-1759

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Phage antibody-display is rapidly maturing into a very effective tool for antibody generation. The recent development of large primary antibody libraries enables selection of antibodies against most targets in under two weeks and many of these antibodies have relatively high (nanomolar) affinities.