Phage antibody-display is rapidly maturing into a very effective tool for antibody generation. The recent development of large primary antibody libraries enables selection of antibodies against most targets in under two weeks and many of these antibodies have relatively high (nanomolar) affinities.
Phage display selection of EGFR-specific antibodies by capture-sandwich panning
β Scribed by Min Kyung Ki; Kyung Jae Kang; Hyunbo Shim
- Book ID
- 107638132
- Publisher
- The Korean Society for Biotechnology and Bioengineering
- Year
- 2010
- Tongue
- English
- Weight
- 413 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1226-8372
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The generation of new antibodies for diagnostic applications using phage display could greatly decrease the time and expense of new assay development but, to be effective, the process must yield antibodies with desired specificity and affinity comparable to those obtained by monoclonal antibody tech
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