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An alternate geometry for the catalytic triad of serine proteases

✍ Scribed by Corey, David R.; McGrath, Mary E.; Vasquez, John R.; Fletterick, Robert J.; Craik, Charles S.


Book ID
127065523
Publisher
American Chemical Society
Year
1992
Tongue
English
Weight
848 KB
Volume
114
Category
Article
ISSN
0002-7863

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A serine protease triad forms the cataly
✍ Turkenburg, Johan P.; Christiansen, Lars; Huge-Jensen, Birgitte; Norskov, Leif; πŸ“‚ Article πŸ“… 1990 πŸ› Nature Publishing Group 🌐 English βš– 341 KB

True lipases attach triacylglycerols and act at an oil-water interface; they constitute a ubiquitous group of enzymes catalysing a wide variety of reactions, many with industrial potential. But so far the three-dimensional structure has not been reported for any lipase. Here we report the X-ray stru