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A serine protease triad forms the catalytic centre of a triacylglycerol lipase

✍ Scribed by Turkenburg, Johan P.; Christiansen, Lars; Huge-Jensen, Birgitte; Norskov, Leif; Brady, Leo; Brzozowski, Andrzej M.; Derewenda, Zygmunt S.; Dodson, Eleanor; Dodson, Guy; Tolley, Shirley


Book ID
109762836
Publisher
Nature Publishing Group
Year
1990
Tongue
English
Weight
341 KB
Volume
343
Category
Article
ISSN
0028-0836

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A serine protease triad forms the cataly
✍ Turkenburg, Johan P.; Christiansen, Lars; Huge-Jensen, Birgitte; Norskov, Leif; πŸ“‚ Article πŸ“… 1990 πŸ› Nature Publishing Group 🌐 English βš– 341 KB

True lipases attach triacylglycerols and act at an oil-water interface; they constitute a ubiquitous group of enzymes catalysing a wide variety of reactions, many with industrial potential. But so far the three-dimensional structure has not been reported for any lipase. Here we report the X-ray stru