A new alkyne protecting group, trispyrazolylborateplatinum(methyl) (TPM), that can tolerate various reaction conditions and is particularly useful for electron-deficient acetylenes allows for synthetic manipulations of polyfunctional acetylenes. This protecting group withstands a variety of reaction
An alkyne protecting group
β Scribed by K.M. Nicholas; R. Pettit
- Book ID
- 104248136
- Publisher
- Elsevier Science
- Year
- 1971
- Tongue
- French
- Weight
- 168 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
Due to the greater reactivity of triple bonds to several of the more common addition reactions, (i.e. reduction, 1 hydroboration,2 and acid-catalyzed hydration3) it is generally very difficult to selectively induce double bonds to undergo addition in the presence of triple bonds. We report
π SIMILAR VOLUMES
This New Edition Incorporates The Significant Developments In The Field Since Publication Of The Third Edition In 1998, Including: New Protective Groups Such As The Fluorous Family And The Uniquely Removable 2-methoxybenzenesulfonyl Group For The Protection Of Amines; New Techniques For The Formatio