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Amplification of the proto-oncogenes int-2, c-erbB-2 and c-myc in human breast cancer

✍ Scribed by Samuel V. Machotka; Carleton T. Garrett; Arnold M. Schwartz; Robert Callahan

Book ID
115826395
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
988 KB
Volume
184
Category
Article
ISSN
0009-8981

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Amplification of the int-2 oncogene was measured in a series of breast tumours and related to amplification of the c-myc and c-erbB-2 oncogenes, histopathological features and relapse-free and overall survival. int-2 was amplified in I I%, c-myc in 20% and c-erbB-2 in 27% of the tumours assessed. in