We examined 22 cases of renal-cell carcinoma (RCC) for structural alterations of the epidermal growth factor receptor (ECFR) gene and found gene amplification in one case of high-stag+high-grade RCC. Dot blot analysis of the total RNA from tumorous and normal kidney tissues revealed overexpression o
โฆ LIBER โฆ
Amplification and overexpression of epidermal growth factor receptor gene in human oropharyngeal cancer
โ Scribed by Saranath, Dhananjaya; Panchal, Rekha G; Nair, Rama; Mehta, Ashok R; Sanghavi, Vikram D; Deo, Madhav G
- Book ID
- 121904860
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 726 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0964-1955
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## Abstract The degree of gene amplification for epidermal growth factor receptor (EGFR) and its expression levels were examined in 4 cases of tumor lesions and their cell lines of human squamous cell carcinoma (SCC) of the oral cavity. The amplification was detected in 1 case (ZA), but not signifi