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Amplification and expression of the HMGIC gene in a benign endometrial polyp

✍ Scribed by Paola Dal Cin; Sylke Wanschura; Bernd Kazmierczak; Giovanni Tallini; Angelo Dei Tos; Jörn Bullerdiek; Ivo Van den Berghe; Philippe Moerman; Herman Van den Berghe

Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
309 KB
Volume
22
Category
Article
ISSN
1045-2257

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✦ Synopsis

In a totally benign endometrial polyp, double minute chromosomes were shown to contain an amplified and apparently nonrearranged HMGIC gene, expressed in the tumor cells, suggesting amplification of HMGIC through double minute chromosome formation as another hitherto unreported mechanism associated with the development of some mesenchymal tumors.

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