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AMP-activated protein kinase regulates PDGF-BB-stimulated interleukin-6 synthesis in osteoblasts: Involvement of mitogen-activated protein kinases

✍ Scribed by Kenji Kato; Takanobu Otsuka; Akira Kondo; Rie Matsushima-Nishiwaki; Hideo Natsume; Osamu Kozawa; Haruhiko Tokuda


Book ID
116720108
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
406 KB
Volume
90
Category
Article
ISSN
0024-3205

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We previously showed that basic fibroblast growth factor (bFGF)-induced activation of protein kinase C (PKC) via phosphatidylinositol-hydrolyzing phospholipase C and phosphatidylcholine-hydrolyzing phospholipase D suppresses interleukin-6 (IL-6) synthesis by bFGF itself in osteoblast-like MC3T3-E1 c