Amniocyte clones for prenatal cytogenetics
โ Scribed by Hecht, F. ;Peakman, D. C. ;Kaiser-McCaw, B. ;Robinson, A.
- Book ID
- 101440321
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 215 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0148-7299
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โฆ Synopsis
Abstract
Amniotic fluid cells were processed in situ on coverslips in 1,429 consecutive cases from Colorado and Arizona. Two true chromosome mosaics were differentiated from 39 pseudomosaics with clarity by the method described here in detail. The culture failure rate was 1โ2% and the error rate was 0% in both laboratories. The time in culture prior to the initial harvest for the last 329 cases was 8.7 days.
๐ SIMILAR VOLUMES
A prospective pilot study for early amniocentesis was conducted over 4 years including 279 early amniocenteses (EAs at 10-14 weeks' gestation) and 181 mid-trimester amniocenteses (MAs at 15 weeks upwards). The study was performed with EA and MA utilizing the same proceduralists, techniques, and cyto