## Abstract Amniotic fluid cells were processed in situ on coverslips in 1,429 consecutive cases from Colorado and Arizona. Two true chromosome mosaics were differentiated from 39 pseudomosaics with clarity by the method described here in detail. The culture failure rate was 1โ2% and the error rate
In situ method for prenatal cytogenetics
โ Scribed by Chen, Andrew T. L. ;Reidy, John A. ;Opitz, John M.
- Book ID
- 101441333
- Publisher
- John Wiley and Sons
- Year
- 1982
- Tongue
- English
- Weight
- 152 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0148-7299
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## Prenatal Exclusion of UPD from Cytogenetic Slides: A Simple Method The growing awareness of the effects of uniparental disomy (UPD) of several chromosomes on phenotype and the knowledge of many conditions at risk for UPD, such as Robertsonian translocations or confined placental mosaicism, has
## Abstract We have had experience with over 300 amniotic fluid specimens for prenatal diagnosis for the fragile X chromosome [fra(X)], and the flask method of tissue culture has been routinely utilized requiring extended tissue culture periods of 3โ4 weeks. The use of the in situ clonal method of