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Ammonia Neurotoxicity: Role of the Mitochondrial Permeability Transition

โœ Scribed by K. V. Rama Rao; A. R. Jayakumar; M. D. Norenberg

Book ID
110441859
Publisher
Springer
Year
2003
Tongue
English
Weight
208 KB
Volume
18
Category
Article
ISSN
0885-7490

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## Abstract Ammonia is a toxin that has been strongly implicated in the pathogenesis of hepatic encephalopathy (HE), and the astrocyte appears to be the principal target of ammonia toxicity. The specific neurochemical mechanisms underlying HE, however, remain elusive. One of the suggested mechanism