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Ammonia Neurotoxicity and the Mitochondrial Permeability Transition

โœ Scribed by M. D. Norenberg; K. V. Rama Rao; A. R. Jayakumar

Book ID
111591607
Publisher
Springer US
Year
2004
Tongue
English
Weight
267 KB
Volume
36
Category
Article
ISSN
0145-479X

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## Abstract Ammonia is a toxin that has been strongly implicated in the pathogenesis of hepatic encephalopathy (HE), and the astrocyte appears to be the principal target of ammonia toxicity. The specific neurochemical mechanisms underlying HE, however, remain elusive. One of the suggested mechanism