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Aminopeptidase B (EC 3.4.11.6)

โœ Scribed by Thierry Foulon; Sandrine Cadel; Paul Cohen


Book ID
117756605
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
121 KB
Volume
31
Category
Article
ISSN
1357-2725

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Aminopeptidase N (APN)/CD13 (EC 3.4.11.2) is a transmembrane protease present in a wide variety of human tissues and cell types (endothelial, epithelial, fibroblast, leukocyte). APN/CD13 expression is dysregulated in inflammatory diseases and in cancers (solid and hematologic tumors). APN/CD13 serve