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Aminopeptidase-N/CD13 (EC 3.4.11.2) Inhibitors: Chemistry, Biological Evaluations, and Therapeutic Prospects

✍ Scribed by Brigitte Bauvois; Daniel Dauzonne


Book ID
101988426
Publisher
John Wiley and Sons
Year
2006
Weight
8 KB
Volume
37
Category
Article
ISSN
0931-7597

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Aminopeptidase-N/CD13 (EC 3.4.11.2) inhi
✍ Brigitte Bauvois; Daniel Dauzonne πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 531 KB

Aminopeptidase N (APN)/CD13 (EC 3.4.11.2) is a transmembrane protease present in a wide variety of human tissues and cell types (endothelial, epithelial, fibroblast, leukocyte). APN/CD13 expression is dysregulated in inflammatory diseases and in cancers (solid and hematologic tumors). APN/CD13 serve