Aminonucleoside of puromycin: Elimination of nephrotoxicity by acetylation of the aminoribose moiety
β Scribed by C.S. Alexander; H.T. Nagasawa
- Book ID
- 115768741
- Publisher
- Elsevier Science
- Year
- 1964
- Tongue
- English
- Weight
- 319 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0006-2952
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## Abstract Aminonucleoside (AMS) inhibited the cell cycle of human lung fibroblasts at a point in G1 phase and at another point in G2 phase. Even when this inhibition was fully established, DNA synthesis and mitosis which were in progress proceeded normally. Inhibition of RNA synthesis in the cult
This study examined the protective effect of two natural antioxidants, ginsenoside Rb-1 and quercetin, on acute nephrosis induced by puromycin aminonucleoside (PA). The protective action of Rb-1 and quercetin were evidenced by their ability to suppress the formation of phosphatidylcholine hydroperox