Aminoglycoside Microarrays To Study Antibiotic Resistance
β Scribed by Matthew D. Disney; Sophie Magnet; John S. Blanchard; Peter H. Seeberger
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 127 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0044-8249
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## Abstract ^1^H NMR spectroscopy was used to determine the conformations of the aminoglycoside antibiotic __N__βdemethylclindamycin and two of its cyclic derivatives. The conformational features of these systems were determined by consideration of vicinal coupling constants and, in some cases, nuc
The effect of ~,eral aminoglycmide (AG) antibiotic8 on aqueous muitilamellar dispersions of mixtures of phosphatid~linositoi (PI) and deuterated phmphafidylcholine (PC') has been studied by deuterium (2H) NMR. Isepandcin and amikachl gave rise to no significant changes in 2H-NMR fineshape relative t