Amino Steroids - Conanine and Heteroconanine Derivatives
β Scribed by G. van De Woude; L. van Hove
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 2010
- Weight
- 500 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0037-9646
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π SIMILAR VOLUMES
## Abstract The title amino steroids have been synthesized from hecogenine acetate 10. The known convenient route for the synthesis of conanine derivatives involving as the key step a HofmannβLoeffler cyclization in a 20aβmethylaminopregnane structure revealed successful in the present case where t
A series of amino acid derivatives of cholesterol, 9a-fluorohydrocortisone, 6u-fluoro-16a-hydroxycortisone-16,17-acetonide, and 2a-methyl-5cr-dihydrotestosterone have been synthesized in a further attempt to provide compounds with increased a ueous solubility. The ac lable hydrosy group of the stero