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Amino- and amido-tetrabenazine derivatives: Synthesis and evaluation as potential ligands for the vesicular monoamine transporter

✍ Scribed by Daniel J. Canney; Mei-Ping Kung; Hank F. Kung

Book ID
116171993
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
989 KB
Volume
22
Category
Article
ISSN
0969-8051

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πŸ“œ SIMILAR VOLUMES

Synthesis and preliminary evaluation of
Synthesis and preliminary evaluation of an iodovinyl-tetrabenazine analog as a marker for the vesicular monoamine transporter
✍ Daniel J. Canney; Yu-Zhi Guo; Mei-Ping Kung; Hank F. Kung πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 French βš– 718 KB

## Abstract A derivative of tetrabenazine (TBZ, __1__) containing an iodovinyl group (I‐TBZ, __3b__) was prepared as a potential radiotracer for the vesicular monoamine transporter. The synthesis of __3a__ was achieved by ethynylation of TBZ. The ethynyl derivative __4__, was converted to the corre