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Amines as leaving groups in nucleophilic aromatic substitution reactions

โœ Scribed by De Vargas, Elba B.; De Rossi, Rita H.; Veglia, Alicia V.

Book ID
125944921
Publisher
American Chemical Society
Year
1986
Tongue
English
Weight
643 KB
Volume
51
Category
Article
ISSN
0022-3263

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Imidazole as leaving group in aromatic n
Imidazole as leaving group in aromatic nucleophilic substitution reactions
โœ Elba B. de Vargas; Rita H. de Rossi ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 213 KB

The reaction of N-(2,4,6\_trinitrophenyl) imidazole with n-butylamine is pH dependent. A mechanism involving acid catalyzed leaving group departure is suggested.