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Solvent-Controlled Leaving-Group Selectivity in Aromatic Nucleophilic Substitution

โœ Scribed by Hintermann, Lukas; Masuo, Ritsuki; Suzuki, Keisuke

Book ID
120659096
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
274 KB
Volume
10
Category
Article
ISSN
1523-7060

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๐Ÿ“œ SIMILAR VOLUMES

Imidazole as leaving group in aromatic n
Imidazole as leaving group in aromatic nucleophilic substitution reactions
โœ Elba B. de Vargas; Rita H. de Rossi ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 213 KB

The reaction of N-(2,4,6\_trinitrophenyl) imidazole with n-butylamine is pH dependent. A mechanism involving acid catalyzed leaving group departure is suggested.