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Chiral leaving groups induce asymmetry in syntheses of binaphthyls in nucleophilic aromatic substitution reactions

โœ Scribed by Wilson, Janet M.; Cram, Donald J.


Book ID
120285791
Publisher
American Chemical Society
Year
1982
Tongue
English
Weight
519 KB
Volume
104
Category
Article
ISSN
0002-7863

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Imidazole as leaving group in aromatic n
โœ Elba B. de Vargas; Rita H. de Rossi ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 213 KB

The reaction of N-(2,4,6\_trinitrophenyl) imidazole with n-butylamine is pH dependent. A mechanism involving acid catalyzed leaving group departure is suggested.