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AMIDE FORMATION FROM ESTERS OF SECONDARY ALKYL MALONIC ACIDS

✍ Scribed by Dox, Arthur W.; Yoder, Lester


Book ID
126438155
Publisher
American Chemical Society
Year
1922
Tongue
English
Weight
280 KB
Volume
44
Category
Article
ISSN
0002-7863

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A new type of amide formation from thioc
✍ Sang-Don Park; Jung-Hee Oh; Dongyeol Lim πŸ“‚ Article πŸ“… 2002 πŸ› Elsevier Science 🌐 French βš– 61 KB

We studied the coupling of thiocarboxylic acid and alkyl azide using various triaryl phosphines. Amide formation greater than 95% was achieved when the free-formation of Staudinger intermediate with electron deficient triaryl phosphines was employed.