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A new type of amide formation from thiocarboxylic acid and alkyl azide

✍ Scribed by Sang-Don Park; Jung-Hee Oh; Dongyeol Lim

Publisher
Elsevier Science
Year
2002
Tongue
French
Weight
61 KB
Volume
43
Category
Article
ISSN
0040-4039

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✦ Synopsis

We studied the coupling of thiocarboxylic acid and alkyl azide using various triaryl phosphines. Amide formation greater than 95% was achieved when the free-formation of Staudinger intermediate with electron deficient triaryl phosphines was employed.

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