Synthesis of Certain α-Amino Acid Esters from Malonic Ester 1
✍ Scribed by Shivers, Joseph C.; Hauser, Charles R.
- Book ID
- 127191163
- Publisher
- American Chemical Society
- Year
- 1947
- Tongue
- English
- Weight
- 260 KB
- Volume
- 69
- Category
- Article
- ISSN
- 0002-7863
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Enantioselective syntheses of optically active or-amino acids from glycine t-butyl ester through Schiff base employing (+)-N-alkyl-10-camphorsulfonamides as chiral auxiliaries were described. Methylation of Schiff base 5 gave high asymmetric inductions, whereas ethylation, allylation and benzylation