Alveolar bone osteoblast differentiation and Runx2/Cbfa1 expression
β Scribed by Hiran Perinpanayagam; Thomas Martin; Vartika Mithal; Mouhammad Dahman; Nancy Marzec; Judith Lampasso; Rosemary Dziak
- Book ID
- 113465740
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 211 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0003-9969
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π SIMILAR VOLUMES
The runt family transcription factor (AML-3/PEBP2alphaA1/Cbfa1/RUNX2) plays a crucial role in formation of the mineralized skeleton during embryogenesis and regulates maturation of the osteoblast phenotype. Because steroid hormones and growth factors significantly influence growth and differentiatio
## Abstract Identifying the genetic pathways that regulate skeletal development is necessary to correct a variety of cartilage and bone abnormalities. The Runx family of transcription factors play a fundamental role in organ development and cell differentiation. Initial studies have shown that both