𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Inhibition of Osf2/Cbfa1 expression and terminal osteoblast differentiation by PPARγ2

✍ Scribed by Beata Lecka-Czernik; Igor Gubrij; Elena J. Moerman; Oumitana Kajkenova; David A. Lipschitz; Stavros C. Manolagas; Robert L. Jilka

Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
384 KB
Volume
74
Category
Article
ISSN
0730-2312

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Expression and regulation of Runx2/Cbfa1
Expression and regulation of Runx2/Cbfa1 and osteoblast phenotypic markers during the growth and differentiation of human osteoblasts
✍ Michelle Prince; Chaitali Banerjee; Amjad Javed; Jack Green; Jane B. Lian; Gary 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 960 KB

The runt family transcription factor (AML-3/PEBP2alphaA1/Cbfa1/RUNX2) plays a crucial role in formation of the mineralized skeleton during embryogenesis and regulates maturation of the osteoblast phenotype. Because steroid hormones and growth factors significantly influence growth and differentiatio

Ghrelin inhibits early osteogenic differ
Ghrelin inhibits early osteogenic differentiation of C3H10T1/2 cells by suppressing Runx2 expression and enhancing PPARγ and C/EBPα expression
✍ Sang Wan Kim; Ok Kyung Choi; Ju Yeon Jung; Jae-Yeon Yang; Sun Wook Cho; Chan Soo 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 266 KB

## Abstract Ghrelin is a 28‐residue peptide identified in the stomach as an endogenous ligand of the growth hormone secretagogue receptor that is expressed in a variety of peripheral tissues, as well as in the brain. In previous studies, ghrelin has been shown to stimulate both adipogenic different

T-box 3 negatively regulates osteoblast
T-box 3 negatively regulates osteoblast differentiation by inhibiting expression of osterix and runx2
✍ K.E. Govoni; G.R. Linares; S-T. Chen; S. Pourteymoor; S. Mohan 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 267 KB 👁 1 views

## Abstract T‐box (Tbx)3, a known transcriptional repressor, is a member of a family of transcription factors, which contain a highly homologous DNA binding domain known as the Tbx domain. Based on the knowledge that mutation of the Tbx3 gene results in limb malformation, Tbx3 regulates osteoblast

Differential regulation of Cbfa1/Runx2 a
Differential regulation of Cbfa1/Runx2 and osteocalcin gene expression by vitamin-D3, dexamethasone, and local growth factors in primary human osteoblasts
✍ Volker Viereck; Heide Siggelkow; Simone Tauber; Dirk Raddatz; Norbert Schutze; M 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 126 KB 👁 1 views

Core binding factor alpha 1 (Cbfa1) is an osteoblast-specific transcription factor essential to develop a mature osteoblast phenotype. However, its exact role in the signaling of various osteotropic-differentiating agents is still unclear. In this study, we assessed the effects of 1,25-(OH)(2)-D3 (D

Differential expression of Id genes in m
Differential expression of Id genes in multipotent myeloid progenitor cells: Id-1 is induced by early- and late-acting cytokines while Id-2 is selectively induced by cytokines that drive terminal granulocytic differentiation
✍ Cathleen L. Cooper; Peter E. Newburger 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 140 KB 👁 2 views

Hematopoietic development is regulated by a complex mixture of cytokine growth factors that guide growth and differentiation of progenitor cell populations at different stages in their development. The genetic programs that drive this process are controlled at the molecular level by the type and num