Alternative pathway of transcriptional induction of p21WAF1/Cip1 by cyclosporine A in p53-deficient human glioblastoma cells
β Scribed by Agata Zupanska; Alicja Adach; Magdalena Dziembowska; Bozena Kaminska
- Book ID
- 113528059
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 494 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0898-6568
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract __SDI1__ is an inhibitor of DNA synthesis that we isolated by expression screening cDNAs prepared from senescent, terminally nondividing human cells. Other groups then cloned this gene as a cyclinβdependent kinase (cdk)βinteracting protein (CIP1, p21) that inhibits cdks; the gene was al
## Abstract Butyric acid is well recognized as a histone deacetylase (HDAC) inhibitor, and changes in histone acetylation are thought to alter gene expression. The mechanism by which sodium butyrate (NaB) induces p21^WAF1/CIP1^, a critical gene involved in the antiproliferative effect of NaB, was s