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Altered ratios and different subcellular distribution of type I and type II cAMP-dependent protein kinases in several thyroidal pathological tissues

✍ Scribed by M. Pavlovic-Hournac; D. Delbauffe; R. Ohayon; P. Wadeleux; R. Winand


Book ID
115912460
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
320 KB
Volume
125
Category
Article
ISSN
0014-5793

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Localization of the regulatory subunit of cAMP-dependent protein kinase type II was studied in proliferating and quiescent fibroblasts 3T3 and in a cell line of neural origin pheochromocytoma PC12. In actively proliferating PC12 cells the regulatory subunit was found to be localized in the nucleus.