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Alterations of K-ras, p53, and erbB-2/neu in human lung adenocarcinomas


Book ID
122919049
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
138 KB
Volume
11
Category
Article
ISSN
0169-5002

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Carcinogen exposure, p53 alteration, and
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BACKGROUND. Synchronous multiple primary lung tumors (SMPLT) have been estimated to occur in 1% of lung carcinoma patients. Criteria for SMPLT diagnosis include different cancer histologies, location in different lobes of the lung, or genetic discordance. Patients with SMPLT have a poor clinical pro