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Localized adenocarcinoma of the lung: Oncogene expression of erbB-2 and p53 in 150 patients


Book ID
123214600
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
261 KB
Volume
13
Category
Article
ISSN
0169-5002

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The lung carcinoma cell line Calu3, which overexpresses the c-erbB-2 oncogene, was stably transfected with antisense (AS) cDNA constructs encompassing different regions of the c-erbB-2 gene. Transfected cells were analyzed for their tumorigenic properties in vitro and in nude mice. Two independent c