We have observed and defined morphometrically and histochemically groups of undifferentiated columnar cells within the surface epithelium in colorectal mucosa. They were present within both non-polypoid and polypoid mucosa in familial adenomatous polyposis, and within non-hereditary adenomatous poly
β¦ LIBER β¦
Alterations of cell kinetics in familial adenomatous polyposis and sporadic colorectal adenoma and carcinoma
β Scribed by Keigo Yoshinaga; Yange Zhang; Takeo Iwama; Chihiro Ono; Masahiro Toyooka; Kenichi Sugihara
- Book ID
- 119425373
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 167 KB
- Volume
- 118
- Category
- Article
- ISSN
- 0016-5085
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## Abstract DNA repair failure is known to be a critical event during carcinogenesis of colorectal cancers. To investigate whether __O__^6^βmethylguanineβDNA methyltransferase (__MGMT__) is altered during colorectal carcinogenesis, we performed immunohistochemical staining on 265 sporadic colorecta