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Multiple colorectal adenomas, familial adenomatous polyposis and germline mutations in MYH

✍ Scribed by Lara Lipton VI; Oliver M. Sieber; Michael Crabtree; Karl Heinimann; Paulo Fidalgo; Robin K.S. Phillips; Marie-Luise Bisgaard; Torben F. Ornoft; Lauri A. Aaltonen; Shirley V. Hodgson; Ian P.M. Tomlinson; Huw J.W. Thomas

Book ID
119427083
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
181 KB
Volume
124
Category
Article
ISSN
0016-5085

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Germline MUTYH (MYH) mutations in Portug
Germline MUTYH (MYH) mutations in Portuguese individuals with multiple colorectal adenomas
✍ GlΓ³ria Isidro; Francisco Laranjeira; Ana Pires; JΓΊlio Leite; Fernando Regateiro; πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 73 KB

Germinal mutations in the base excision repair (BER) gene MUTYH (MYH) have recently been described in association with predisposition to multiple colorectal adenomas and cancer. In contrast to the classic dominant condition of familial adenomatous polyposis (FAP) due to germinal mutations in the APC

Undifferentiated columnar cells in color
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