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Alterations in the tumor suppressor genep16INK4Aare associated with aggressive behavior of penile carcinomas

✍ Scribed by Micaela Poetsch; Martin Hemmerich; Christoph Kakies; Britta Kleist; Eduard Wolf; Frank vom Dorp; Oliver W. Hakenberg; Chris Protzel

Book ID
106118326
Publisher
Springer
Year
2010
Tongue
English
Weight
602 KB
Volume
458
Category
Article
ISSN
1432-2307

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Expression of p16INK4A and alterations of the 9p21-23 chromosome region in non-small-cell lung carcinomas: Relationship with tumor growth parameters and ploidy status
✍ George Mariatos; Vassilis G. Gorgoulis; Panayotis Zacharatos; Athanassios Kotsin πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 French βš– 286 KB πŸ‘ 1 views

The 9p21-23 chromosome region harbors a number of known and putative tumor-suppressor genes (TSGs). The best characterized gene in this area is p16 INK4A (CDKN2A). Alterations of its product have been observed in various malignancies, including non-small-cell lung carcinomas (NSCLCs). We earlier inv