Loss of heterozygosity at 10q in tumors
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Daniela Gasparotto; Tamara Vukosavljevic; Sara Piccinin; Luigi Barzan; Sandro Su
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Article
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1999
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John Wiley and Sons
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French
β 114 KB
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Frequent loss of a specific chromosomic region in cancers is often associated with inactivation of a tumor-suppressor gene. The long arm of chromosome 10 is deleted in several types of tumor, among them squamous-cell carcinomas of the head and neck (HNSCC). To determine the role of 10q deletions in