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Alteration of the pattern of hippocampal nerve cell RNA labelling during training in rats

✍ Scribed by Aroldo Cupello; Holger Hyde´n

Book ID
118863217
Publisher
Elsevier Science
Year
1976
Tongue
English
Weight
436 KB
Volume
114
Category
Article
ISSN
0006-8993

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Studies on RNA metabolism in the nerve c
Studies on RNA metabolism in the nerve cells of Hippocampus during training in rats
✍ A. Cupello; H. Hydén 📂 Article 📅 1978 🏛 Springer-Verlag 🌐 English ⚖ 510 KB

Direct evidence is presented that training to change behavior initiates synthesis of specific species of mRNA in pyramidal nerve cells of CA3 of the hippocampus in rats. Reversal of handedness was used as goal-directed operant test and active controls. Newly synthesized poly(A) associated mRNA with

Pattern of labeling of poly (A)-associat
Pattern of labeling of poly (A)-associated RNA in the CA3 region of rat hippocampus during training
✍ Aroldo Cupello; Professor Holger Hydén 📂 Article 📅 1976 🏛 John Wiley and Sons 🌐 English ⚖ 317 KB

## Abstract Newly synthesized poly (A)‐associated mRNA was analysed in the hippocampal CA~3~ pyramidal nerve cells in rats subjected to training to reverse handedness. The nerve cells of trained animals showed a smaller percentage of poly (A)‐associated mRNA than did the active controls. However,