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Studies on RNA metabolism in the nerve cells of Hippocampus during training in rats

✍ Scribed by A. Cupello; H. Hydén

Book ID
104676319
Publisher
Springer-Verlag
Year
1978
Tongue
English
Weight
510 KB
Volume
31
Category
Article
ISSN
0014-4819

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✦ Synopsis

Direct evidence is presented that training to change behavior initiates synthesis of specific species of mRNA in pyramidal nerve cells of CA3 of the hippocampus in rats. Reversal of handedness was used as goal-directed operant test and active controls. Newly synthesized poly(A) associated mRNA with S value of 25 and a stimulation of poly(A) lacking mRNA of 8--9 S and 16--17 S were found in the CA3 nerve cells of trained but not in active controls.

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