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Pattern of labeling of poly (A)-associated RNA in the CA3 region of rat hippocampus during training

✍ Scribed by Aroldo Cupello; Professor Holger Hydén

Publisher
John Wiley and Sons
Year
1976
Tongue
English
Weight
317 KB
Volume
2
Category
Article
ISSN
0360-4012

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✦ Synopsis

Abstract

Newly synthesized poly (A)‐associated mRNA was analysed in the hippocampal CA~3~ pyramidal nerve cells in rats subjected to training to reverse handedness.

The nerve cells of trained animals showed a smaller percentage of poly (A)‐associated mRNA than did the active controls. However, a specific fraction of this poly (A) hippocampal RANA with a S~E~ value of around 25 was reproducibly stimulated. This qualitative nerve cell mRNA change is discussed in relation to similar changes in the protein pattern as a function of training.

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