Alpha globin gene duplications in beta thalassemia patients with intact beta globin gene
✍ Scribed by Valeria Faà; Maddalena Masala; Antonio Cao; Maria Cristina Rosatelli
- Book ID
- 116304740
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 358 KB
- Volume
- 44
- Category
- Article
- ISSN
- 1079-9796
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Haplotype frequencies for the beta-globin gene cluster were determined in 96 chromosomes from a Venezuelan mixed population. Twelve haplotypes were observed, the most frequent of which were 2, 3, and 4; all others showed prevalences below 10%. When the results were compared with those of 13 other gr
Haplotypes derived from five polymorphic restriction sites in the beta-globin gene cluster were investigated in 139 individuals from five different Brazilian Indian tribes by the polymerase chain reaction (PCR). Eight haplotypes were identified. Haplotypes 2 (+ ----1 and 6 (-+ + -+) were the most