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Allyl isothiocyanate: Comparative disposition in rats and mice

โœ Scribed by Y.M. Ioannou; L.T. Burka; H.B. Matthews

Book ID
113206330
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
769 KB
Volume
75
Category
Article
ISSN
0041-008X

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Allyl isothiocyanate (AITC) was given in doses of 0, 10, 20, or 40 mg/kg (5 days/week) by oral intubation to male rats for up to 6 weeks. The highest dosage level caused a decrease in body weight, thymus weight, blood glucose and serum globulin levels. Haematological examination revealed an increase