✦ LIBER ✦

Allometric Pharmacokinetic Scaling: Towards the Prediction of Human Oral Pharmacokinetics

✍ Scribed by Meihua Rose Feng; Xiaochun Lou; Richard R. Brown; Athiwat Hutchaleelaha

Book ID: 110251041
Publisher: Springer US
Year: 2000
Tongue: English
Weight: 697 KB
Volume: 17
Category: Article
ISSN: 0724-8741
DOI: 10.1023/a:1007520818956

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Allometric prediction of the human pharm

Allometric prediction of the human pharmacokinetic parameters for naveglitazar

✍ Preeti Ahlawat; Nuggehally R. Srinivas 📂 Article 📅 2008 🏛 Springer-Verlag 🌐 English ⚖ 475 KB

The application of allometric scaling pr

The application of allometric scaling principles to predict pharmacokinetic parameters across species

✍ Huang, Qingbiao; Riviere, Jim E 📂 Article 📅 2014 🏛 Informa plc 🌐 English ⚖ 532 KB

The allometric approach for interspecies

The allometric approach for interspecies scaling of pharmacokinetic parameters

✍ W.A. Ritschel; N.N. Vachharajani; R.D. Johnson; A.S. Hussain 📂 Article 📅 1992 🏛 Elsevier Science ⚖ 662 KB

The Authors’ Reply: Obesity and Allometr

The Authors’ Reply: Obesity and Allometric Scaling of Pharmacokinetics

✍ Jeroen Diepstraten, Catherijne A. J. Knibbe 📂 Article 📅 2011 🏛 Springer International Publishing AG 🌐 English ⚖ 84 KB

Pharmacokinetic allometric scaling of an

Pharmacokinetic allometric scaling of antibodies: Application to the first-in-human dose estimation

✍ Iftekhar Mahmood 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 140 KB 👁 1 views

The objectives of this study are: (i) to evaluate the predictive performance of interspecies scaling for antibodies to predict clearance, volume of distribution at steady state, and half-life in humans from animal data and (ii) to estimate first-inhuman dose based on the predicted human clearance. F

Pharmacokinetic scale-up: Accurate predi

Pharmacokinetic scale-up: Accurate prediction of human pharmacokinetic profiles from animal data

✍ Joyce Mordenti 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 English ⚖ 318 KB