Pharmacokinetic allometric scaling of an
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Iftekhar Mahmood
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Article
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2009
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John Wiley and Sons
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English
โ 140 KB
๐ 1 views
The objectives of this study are: (i) to evaluate the predictive performance of interspecies scaling for antibodies to predict clearance, volume of distribution at steady state, and half-life in humans from animal data and (ii) to estimate first-inhuman dose based on the predicted human clearance. F