2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine (PhIP), a compound found in cooked meat, is a mammary gland carcinogen in female Sprague-Dawley rats. PhIP-induced rat mammary gland carcinomas were examined for mutations in several genes (exons) known to regulate cell growth and apoptosis, including
Allelic imbalance and altered expression of genes in chromosome 2q11–2q16 from rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
✍ Scribed by Qiu, Cunping; Yu, Minshu; Shan, Liang; Snyderwine, Elizabeth G
- Book ID
- 110067351
- Publisher
- Nature Publishing Group
- Year
- 2003
- Tongue
- English
- Weight
- 340 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0950-9232
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