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Allelic Deletion Mapping of Putative Tumor Suppressor Genes on 17q in Sporadic Ovarian Cancer

✍ Scribed by Chen, Kuang-Chao ;Hsieh, T'sang-T'ang ;Schwartz, Peter E. ;Yang-Feng, Teresa L.


Book ID
119845092
Publisher
Wiley (Blackwell Publishing)
Year
1995
Weight
504 KB
Volume
21
Category
Article
ISSN
1340-9654

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## Abstract Allelic imbalance on chromosome arm 22q has been detected in 50–70% of ovarian cancers, suggesting the presence of a tumor‐suppressor gene on this chromosome arm that is involved in ovarian carcinogenesis. Recently, we isolated a candidate tumor‐suppressor gene, __MYO18B__, at 22q12.1,