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Alkylation and condensation reactions of N,N-dibenzylglycine esters: synthesis of ?-amino acid derivatives

✍ Scribed by Gray, Brian D.; Jeffs, Peter W.


Book ID
120159991
Publisher
The Royal Society of Chemistry
Year
1987
Tongue
English
Weight
185 KB
Volume
18
Category
Article
ISSN
0022-4936

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## Abstract Esters can be prepared from __N__‐hydroxyphthalimide and __N__‐carbobenzoxy‐ or __N__‐phthaloyl‐amino acids using dicyclohexylcarbodi‐imide as condensing agent. The compounds are suitable for the stepwise synthesis of peptides without racemization. With methanol the __N__‐hydroxyphthali