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N -Alkylation of Amino Acid Esters Using Sodium Triacetoxyborohydride

✍ Scribed by Ramanjulu, Joshi M.; Joullié, Madeleine M.


Book ID
120193649
Publisher
Taylor and Francis Group
Year
1996
Tongue
English
Weight
225 KB
Volume
26
Category
Article
ISSN
0039-7911

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Selective N-monoalkylation of a-amino esters with activated alkyl bromides was studied using various alkali or alkali earth metal bases. In the production of N-monoalkylated amino ester derivatives and suppression of N,N-dialkylation, lithium hydroxide was more effective than any other alkali or alk