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Alkaloidal Constituents of Mucuna pruriens Seeds.

✍ Scribed by Laxminarain Misra; Hildebert Wagner


Publisher
John Wiley and Sons
Year
2005
Weight
12 KB
Volume
36
Category
Article
ISSN
0931-7597

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Mechanism of action of the aqueous seed
✍ M. O. Uguru; J. C. Aguiyi; A. A. Gesa πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 75 KB πŸ‘ 2 views

The hot water extract (HWE) of the seed of Mucuna pruriens dose-dependently contracted the guinea-pig ileum. The ED 50 and pD 2 values for the HWE was lower than those of ACh and histamine. Cyproheptadine and promethazine (10 ng/mL) significantly antagonized the effects of histamine, 5-hydroxytrypta